Frozen plasma


  Frozen plasma, which contains all the coagulation factors, is indicated in the following situations:
  • Reversal of warfarin therapy in the patient with life-threatening bleeding or undergoing emergency surgery. (The treatment should also include a vitamin K supplement.)
  • Active bleeding or major surgery with a PT or PTT 1.5 times normal.
  • Microvascular bleeding or massive transfusion (implying consumption and dilution of coagulation factors, respectively) without readily available PT/PTT results.
  • Patients with liver disease related coagulopathy for certain procedures.
Fresh frozen plasma; ©qscalpel (photo by Adam Szulewski)