Cryoprecipitate is a rich source of fibrinogen and also contains VWF, Factor VIII and XIII. Cryoprecipitate is indicated in the treatment of:
  • Microvascular or massive bleeding in patients with either a clinical picture suggestive of a low fibrinogen concentration (for example DIC); or a confirmed low fibrinogen concentration of less that 0.8 to 1.0 g/L.
  • von Willebrand’s disease or Hemophilia A only if factor concentrates are unavailable and DDAVP is unavailable or ineffective.
Cryoprecipitate; ©qscalpel (photo by Adam Szulewski)