The seronegative spondyloarthropathies are a subgroup of the rheumatic diseases. As the name implies, patients with these diseases test negative for Rheumatoid factor. This group of diseases includes:
- Ankylosing Spondylitis (AS)
- Reactive arthritis
- Enteropathic arthritis
- Psoriatic arthritis
Clinical presentationThe seronegative arthritides may present as an inflammatory arthropathy or as back pain (particularly in patients with AS). When arthritis is associated with psoriasis or inflammatory bowel disease, it may either precede or follow diagnosis of the associated disease.
|Ankylosing spondylitis frequently presents with back pain and stiffness. ©iStockphoto/motoed|